Sze Microspheres : Known Proof of Effectiveness Y - Loaded 90 Based Dosimetry for Liver Cancer Treated Using −
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چکیده
1. Lam MGEH, Goris ML, Iagaru AH, Mittra ES, Louie JD, Sze DY. Prognostic utility of 90Y radioembolization dosimetry based on fusion 99mTc-macroaggregated albumin–99mTc-sulfur colloid SPECT. J Nucl Med. 2013;54:2055–2061. 2. Garin E, Lenoir L, Rolland Y, et al. 99mTc-MAA SPECT/CT based dosimetry accurately predicts tumour response and survival in HCC patients treated with 90Y-loaded glass microspheres: preliminary results. J Nucl Med. 2012;53:255–263. 3. Garin E, Lenoir L, Edeline J, et al. Boosted selective internal radiation therapy with 90Y-loaded glass microspheres (B-SIRT) for hepatocellular carcinoma patients: a new personalized promising concept. Eur J Nucl Med Mol Imaging. 2013;40: 1057–1068. 4. Erdi YE, Wessels BW, Loew MH, et al. Threshold estimation in single photon emission computed tomography and planar imaging for clinical radioimmunotherapy. Cancer Res. 1995;55(23, suppl)5823s–5826s. 5. Garin E, Lenoir L, Rolland Y, et al. Effectiveness of quantitative MAA SPECT/ CT for the definition of vascularized hepatic volume and dosimetric approach: phantom validation and clinical preliminary results in patients with complex hepatic vascularization treated with yttrium-90-labeled microspheres. Nucl Med Commun. 2011;32:1245–1255. 6. Chiesa C, Maccauro M, Romito C, et al. Need, feasibility and convenience of dosimetric treatment planning in liver selective internal radiation therapy with 90Y microspheres. Q J Nucl Med Mol Imaging. 2011;55:168–197. 7. Kao YH, Hock Tan AE, Burgmans MC, et al. Image-guided personalized predictive dosimetry by artery-specific SPECT/CT partition modeling for safe and effective 90Y radioembolization. J Nucl Med. 2012;53:559–566. 8. Flamen P, Vanderlinde B, Delatte P, et al. Multimodality imaging can predict the metabolic response of unresectable colorectal liver metastases to radioembolization therapy with yttrium-90 labeled resin microspheres. Phys Med Biol. 2008; 53:6591–6603. 9. Chiesa C, Lambert B, Maccauro M, et al. Pretreatment dosimetry in HCC radioembolization with 90Y glass microspheres cannot be invalidated with a bare visual evaluation of 99mTc-MAA uptake of colorectal metastases treated with resin microspheres. J Nucl Med. In press. 10. Chiesa C, Miro M, Maccauro M, et al. Comparison of standard versus dosimetrically individualized treatment in intermediated/advanced hepatocellular carcinoma (HCC) radioembolization with glass microspheres. EANM ’13 website. http:// eanm13.eanm.org/abstracts/session_detail.php?sessionNumber51704&referer5/ programme/prog_20131023.php?navId50. Accessed May 27, 2014.
منابع مشابه
90Y Radioembolization of Colorectal Hepatic Metastases Using Glass Microspheres: Safety and Survival Outcomes from a 531-Patient Multicenter Study.
UNLABELLED Hepatic metastases of colorectal carcinoma are a leading cause of cancer-related mortality. Most colorectal liver metastases become refractory to chemotherapy and biologic agents, at which point the median overall survival declines to 4-5 mo. Radioembolization with (90)Y has been used in the salvage setting with favorable outcomes. This study reports the survival and safety outcomes ...
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UNLABELLED The objective of this study was to evaluate the response rate and survival of hepatocellular carcinoma portal vein thrombosis (PVT) patients treated with (90)Y-loaded glass microspheres using a personalized dosimetry and intensification concept. METHODS The microspheres were administered to 41 hepatocellular carcinoma PVT patients (main = 12; lobar/segmental = 29). (99m)Tc-macroagg...
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